OSTENIL® PLUS contains a higher concentration of sodium hyaluronate, with the addition of mannitol. This formulation offers effective symptomatic relief with a single injection in knee and hip joints, and is well tolerated. OSTENIL® PLUS contains 40mg / 2ml sodium hyaluronate, plus mannitol.

OSTENIL® PLUS is a single injection option. Please consult your clinician.

£80.00 (plus P&P + VAT)

OSTENIL® PLUS, like the standard version of OSTENIL®,  is an isotonic solution of highly purified sodium hyaluronate (or hyaluronic acid) developed specifically for the treatment of osteoarthritis. The novel formulation of OSTENIL® PLUS utilises the combination of high concentration of sodium hyaluronate + mannitol. This formulation offers the option to reduce the number of SH injections to only one injection per treatment cycle.

Patients: Please go to the "Patient Information" section for more information on Joint Injections and on How to get OSTENIL.


Clinicians: 
Please go to the "Clinicians" section to view pertinent Clinical Studies and for more information on the Rationale for Viscosupplementation.

Licensed Indication:  Pain and restricted mobility in degenerative and traumatic changes of the knee joint and other synovial joints. 
Reimbursement:  Available on the NHS (FP10); listed in MIMS (Section "Musculoskeletal / Local Injections / Hyaluronate")
Pack Size: 40 mg / 2ml syringe
Dosage: Single injection
Active Ingredient: Sodium hyaluronate 2.0%
Unit Price: £80.00 (plus P&P + VAT)
SmPC:  OSTENIL® PLUS: Instructions for Use 

Inject OSTENIL® PLUS into the affected joint. Several joints may be treated at the same time. Repeat treatment cycles may be administered as required. In case of joint effusion it is advisable to reduce the effusion by aspiration, rest, application of an ice pack and/or intra-articular corticosteroid injection. Treatment with OSTENIL® PLUS can be started two to three days later.

The content and the outer surface of the OSTENIL® PLUS prefilled syringe are sterile as long as the sterile pack remains unbroken. Take the pre-filled syringe out of the sterile pack. Before usage of the pre-filled syringe the tamper-evident seal has to be tilted up. As a result the crosspieces of the tamperevident seal break and the cap can be removed together with the tip cap (see pictures). Attach a suitable needle (for example 18 to 25G) and secure it by turning slightly. If present remove the air bubble from the syringe prior to injection.

  • Ian Andrews, Oakwood Physiotherapy
    5.00 out of 5

    Just to let you know that we have had continued great feedback with your product and all our patients are extremely happy. Many thanks as always.

  • Steve Tappin
    5.00 out of 5

    I'm a large man with health issues and arthritis especially in my knee. Three years ago I was informed I needed a full knee replacement. I said I was concerned about the strength in my legs and my weight for a knee replacement to be successful. I have had Ostenil Plus knee injections for 3 years and I've lost 4 stone and strengthened my legs. The hospital have now delayed my operation and stated that if I lose more weight and continue with my jabs I will further delay my operation and may not need one. If it works for me it will work for anyone.


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